The word liposome comes from the Greek language and means “fat body”. A liposome is a micro fossilized droplet
with a similar structure to our cell membrane, so the active ingredients are more easily absorbed into our body.
Cell membranes are made mainly of amyrophilic molecules. This is a special type of surfactant molecule, which has the property of being composed of a hydrophilic and a hydrophobic part. The polar head attracts water, while the non-polar tail repels water or attracts non-polar solvents. The amphiphilicity causes the heads to turn towards the water, the outer part, and the tails to turn inwards, away from the water. This gives two layers, with the tails sticking together and the heads on the outer layer. Thus, at high lipid concentrations, these bilayers form lamellar liquid crystalline phases where two-dimensional planar lipid bilayers alternate with layers of water. However, at lower lipid concentrations, these bilayers separate to form spheres, which may be monolayers or bilayers. Monolayers are called micelles and bilayers are called liposomes. Thus, liposomes can also trap part of the aqueous phase inside, as they are also on the surface of the inner layer of the polar head. The main components of the liposome membrane are phospholipids and cholesterol. Together with glycolipids and cholesterol, they are the main building blocks of cell membranes and constitute the lipid bilayer. Liposomes can be large (2.5 µm) or small (25 nm) and can consist of one or up to 100 layers. The thickness of the lipid bilayer is around 5 nm. Due to their particle size, ranging from 20 nanometres to a few micrometres, they are classified as nanoparticles. Liposomes are excellent nanometre-sized systems suitable for delivering active substances to specific parts of the body.
Liposomes have proven to be an excellent delivery vehicle for bioactive ingredients in the cosmetic, nutraceutical and pharmaceutical industries due to their biodegradability and bioavailability.
Bioavailability refers to the level and rate at which a substance enters the bloodstream to reach the endpoint of action. High bioavailability means higher therapeutic efficacy of the active substance. The bioavailability of liposomes is around 80%.
The advantages of liposomes over other delivery systems are biodegradability, low toxicity, easily adaptable properties and increased efficacy of the active ingredients.
Liposomal vitamin D3 + K2 contains 50 µg – 2000 IU (1000 % of the ADI/RDA*) of vitamin D3 and 100 µg (133 % of the ADI/RDA*) of vitamin K2. Vitamin D and K contribute to the maintenance of healthy bones. Vitamin D contributes to the immune system and muscle function and to the maintenance of healthy teeth.
Liposomal Vitamin D3 + K2 is free from ethanol, GMOs and sugars.